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Soleno Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the development and commercialization of therapeutics for the treatment of rare diseases. The Company’s lead candidate, Diazoxide Choline Extended-Release tablets (DCCR), a once-daily oral tablet for the treatment of Prader-Willi syndrome (PWS), is being evaluated in a phase III clinical development program. DCCR is a potent ATP-sensitive potassium (KATP) channel activator. DCCR tablets consist of the active ingredient diazoxide choline, a choline salt of diazoxide, which is a benzothiadiazine. DCCR’s mode of action with targets in the brain, pancreas and fat tissue has the potential to broadly impact complex diseases like PWS to reduce appetite, reduce food seeking, improve satiety, improve insulin and leptin resistance, and reduce body fat. The Company has a Fast-Track designation for DCCR in PWS and orphan designation for the drug in the United States and the European Union.
Name | Age | Since | Title |
---|---|---|---|
William G. Harris | 63 | 2014 | Independent Director |
Anish Bhatnagar | 51 | 2014 | President, CEO, COO & Director |
Andrew Sinclair | 49 | 2018 | Independent Director |
Ernest Mario | 82 | 2007 | Independent Chairman |
Thomas B. Casale | - | - | Member of Advisory Board |
Vinod K. Bhutani | - | - | Member of Advisory Board |
David K. Stevenson | - | - | Member of Advisory Board |
Glenis Kathleen Scadding | - | - | Member of Advisory Board |
Robert D. Christensen | - | - | Member of Advisory Board |
Shamim Ruff | 64 | 2024 | Chair of the Development Advisory Board |
Birgitte Volck | 62 | 2019 | Independent Director |
Matthew Pauls | 53 | 2023 | Independent Director |
James Arthur Geraghty | 70 | 2024 | Member of Advisory Board |
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