Glaxo launches late-stage study of mepolizumab in patients with nasal polyps

Seeking Alpha

Published Jun 27, 2017 02:16PM ET

Glaxo launches late-stage study of mepolizumab in patients with nasal polyps

  • GlaxoSmithKline (GSK -0.4%) initiates a Phase 3 clinical trial, SYNAPSE, assessing mepolizumab, an interleukin-5 (IL-5) antagonist, for the treatment of nasal polyps, a chronic inflammatory disorder that leads to the obstruction of the nasal passages from soft tissue growth.
  • The 400-subject study will evaluate the safety and efficacy of 100 mg of mepolizumab, administered every four weeks via pre-filled syringe, for 52 weeks on top of standard-of-care treatment (intranasal corticosteroids).
  • Mepolizumab is currently marketed under brand name NUCALA for the treatment of severe asthma.
  • Now read: 'Major' Reprieve Number Two: Another Stumble For GlaxoSmithKline's Advair Blockbuster Generic US Competition

Original article

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