Data suggests mRNA booster dose generates stronger antibody response after J&J shot - Axios

Reuters

Published Oct 13, 2021 12:35AM ET

(Reuters) - People who received Johnson & Johnson (NYSE:JNJ)'s COVID-19 vaccine will have a stronger neutralizing antibody response if they get an mRNA shot as the second dose, Axios reported https://www.axios.com/coronavirus-vaccine-booster-fda-mix-match-data-2593a8db-6b5e-4333-95e2-4064b2433e42.html?utm_source=twitter&utm_medium=social&utm_campaign=onhrs on Tuesday, citing a person who has seen data collected by the U.S. National Institutes of Health (NIH).

J&J has asked the U.S. Food and Drug Administration (FDA) to approve a shot of its own single-dose vaccine as the booster dose. The FDA's advisers are set to consider the need on Friday.

The NIH will present the mix-and-match data to the FDA panel on Friday, Axios said.

There were limitations to the NIH data, according to the report. Neutralizing antibodies only prevent the virus from entering cells and replicating, and the report said it was unclear how long the response will last.

The NIH, FDA and J&J did not immediately respond to Reuters' requests for comment.

Two-dose vaccines made by Pfizer Inc (NYSE:PFE) and its German partner BioNTech and Moderna (NASDAQ:MRNA) Inc use the mRNA technology.