U.S. CDC advisers mull COVID-19 boosters for immune-compromised people

Reuters

Published Jul 22, 2021 12:47PM ET

Updated Jul 22, 2021 04:16PM ET

By Julie Steenhuysen

CHICAGO (Reuters) -Advisers to the U.S. Centers for Disease Control and Prevention on Thursday will consider evidence suggesting that a booster dose of COVID-19 vaccines could increase protection among people with compromised immune systems.

Data presented ahead of the meeting noted that such people have a reduced antibody response following the recommended primary vaccination series compared with healthy individuals.

"Emerging data suggest that an additional COVID-19 vaccine dose in immunocompromised people enhances antibody response and increases the proportion who respond," slides released ahead of the meeting showed.

The committee is not scheduled to vote on a recommendation for whether to administer additional doses. That could be decided at a later meeting.

In small studies, short-term side effects from a third dose of mRNA vaccines - such as those made by BioNTech/Pfizer Inc or Moderna (NASDAQ:MRNA) Inc - were about the same as those experienced with the first two doses, the CDC said in its presentation.

An estimated 2.7% of U.S. adults live with weakened immune systems, according to the CDC presentation, based on data from 2013. The group includes people living with HIV/AIDS, cancer and people with organ transplants or autoimmune diseases who take drugs to dampen their immune response.

Those individuals are at increased risk of severe disease and death from COVID-19.

Last week, Israel began administering third doses of the Pfizer/BioNTech vaccine to immunocompromised people, including those who have had heart, lung, kidney or liver transplants and cancer patients receiving chemotherapy.

Some experts believe the CDC is nearing a similar recommendation in the United States.