Ebola Drug Developed With Government Funding

International Business Times

Published Aug 07, 2014 10:35AM ET

Ebola Drug Developed With Government Funding

By Meagan Clark - The experimental drug being used to treat two Americans stricken with the Ebola virus while treating patients in Africa was funded in large part by the same U.S. Department of Defense unit that developed the Internet. Kentucky BioProcessing, acquired by cigarette-maker Reynolds American Inc. NYSE:RAI in January, received millions of dollars from the U.S. Defense Department to develop the medicine that may save the lives of missionaries Nancy Writebol and Dr. Kent Brantly.

In 2010, the company received a one-year, $17.9 million contract with the Defense Advanced Research Projects Agency (DARPA) to produce “a proof-of-concept platform capable of yielding a purified vaccine candidate using a whole plant-based process,” with an expected completion date of March 2011, according to the contract.

DARPA was created in 1958 as the Advanced Research Projects Agency (ARPA) to design and execute cutting edge technology. Among its most notable creations are the Internet, stealth plane technology and the U.S. military's m16 assault rifle. 

For the Ebola virus treatment, Kentucky BioProcessing made the drug cocktail called ZMapp for the San Diego-based lab Mapp Biopharmaceutical. ZMapp is a combination of Ebola treatments that contains three antibodies meant to fight the virus once. Scientists took the antibodies from mice exposed to Ebola and genetically altered a tobacco plant strain to produce the antibodies.

Only Kentucky BioProcessing is authorized by the U.S. government to produce ZMapp, and currently, only a handful of doses are available, director of National Institute of Allergy and Infectious Diseases, Anthony Fauci, told CNN Tuesday.