Stock Up 300% In Six Weeks -- But There's More... Right?

 | Sep 05, 2012 02:03AM ET

Sarepta Therapeutics Inc., (SRPT) formerly AVI BioPharma, Inc., is a biopharmaceutical company focused on the discovery and development of ribonucleic acid-based (RNA) therapeutics for the treatment of both rare and infectious diseases.

This is a vol and stock note on a bio-tech with some very interesting news. I'll summarize what's the happs below, then we'll move onto the options and vol. I'll be taking a chunk of this content from a Seeking Alpha article, cited below:

Sarepta Therapeutics (SRPT), formerly known as AVI BioPharma, is closing in on a significant medical breakthrough for the largest segment of Duchenne Muscular Dystrophy sufferers. Duchenne Muscular Dystrophy is an affliction that results in muscle degeneration and certain early death. It affects mostly boys with most sufferers wheelchair dependent by age 12 and a life expectancy of 25 years. There is no known cure for Duchenne Muscular Dystrophy.


Sarepta's stock has been on a tear the last five weeks going from around $4 per share on July 23rd and closing at $15.82 August 31. The catalyst for this move was Sarepta's release of 36-week data of their current phase IIb extension study that, according to Sarepta's CEO Chris Garabedian, showed "statistically significant clinical benefit" in the 6 minute walk test - which is a "clinical meaningful outcome measure" for Duchenne Muscular Dystrophy.

[...] that the lead investigator for the trial is Dr. Jerry Mendell, who is the director of the Centers for Gene Therapy and Muscular Dystrophy at Nationwide Children's Hospital in Columbus, OH. Dr. Mendell stated Sarepta's drug had "an unprecedented treatment effect" on participants in its latest trial.

Sarepta plans to release the full 48-week trial results for the above referenced study in October. If the results are positive as expected, Sarepta will go for accelerated FDA approval. --
Source: Seeking Alpha via Yahoo! Finance; Sarepta surges on new muscular dystrophy drug data .

The stock found a bit of a quiet period following the gap up, but has recently risen again. The stock closed at $10.78 on 8-24-2012 and is now nearly 40% higher in about two weeks.

On the vol side we have a bit murkier of a picture since the stock changed symbols recently. Having said that, we can see that the implied is now at an annual high pushing over 140%. But the news is due out in Oct (probably), and the Skew Tab shows us that.

Let's turn to the Skew Tab to examine the line-by-line and month-to-month vols.