Prima BioMed Initiates Phase-2b Breast Cancer Trial

 | Jan 04, 2016 12:08PM ET

Prima Biomed Ltd. (O:PBMD) has initiated a Phase IIb study of IMP321 in metastatic breast cancer, marking the start of a period of expected strong newsflow from its in-house and partnered LAG-3 programmes in cancer and autoimmune diseases. The trial represents the return to the clinic of IMP321, a soluble LAG-3 fusion protein that doubled the tumour response rate vs chemo alone in Phase IIa, which was acquired with the other LAG-3 programmes with the purchase of Immutep in late 2014. The proceeds of the recent capital raise increase our valuation to A$273m (vs A$271m).