Pfizer Starts Phase Ib For Duchenne Muscular Dystrophy Drug

 | Apr 12, 2018 11:37PM ET

Pfizer Inc. (NYSE:PFE) has announced initiation of dosing in a phase Ib study, evaluating its mini-dystrophin gene therapy candidate, PF-06939926, for the treatment of boys aged from five to 12 years with duchenne muscular dystrophy (DMD). Notably, DMD is a genetic disease characterized by muscle degeneration and weakness. The company anticipates initial data from the study in the first half of 2019.

The phase Ib study is an open-label, non-randomized, ascending dose assessment, to be conducted on approximately 12 boys with DMD. The study is designed to evaluate the safety and tolerability of PF-06939926 and also assess muscle strength, quality and function in a given patient population.

Shares of Pfizer were up almost 1.5% on Apr 12, following the above news release. However, the stock has gained 7.2% in the past year, marginally underperforming the Zacks Investment Research

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