Novartis (NVS) Presents Positive Data On Cardiovascular Drug
Zacks Investment Research | Sep 18, 2016 10:16PM ET
Novartis AG (NYSE:NVS) announces new analysis from the PARADIGM-HF study on its cardiovascular drug, Entresto, at a scientific meeting of the Heart Failure Society of America.
Results from the study demonstrated the benefits of Entresto in heart failure patients with reduced ejection fraction (HFrEF). Patients on Entresto reported higher quality of life scores, compared to those taking ACE inhibitor, enalapril.
Note that Entresto (twice-daily) is used in conjunction with other heart failure therapies for reducing strain on the failing heart. It is indicated in the U.S. for the treatment of heart failure (NYHA class II-IV) in patients with systolic dysfunction. In the EU, the drug is approved for the treatment of symptomatic chronic HFrEF in adult patients.
Novartis is working on expanding Entresto’s label and is evaluating the drug for preserved ejection fraction heart failure conditions.
We remind investors that Entresto received a strong Class I recommendation in both the U.S. and the EU as per heart failure treatment guidelines. These guidelines establish Entresto as the standard of care for symptomatic patients with HFrEF. Drug sales are expected to be approximately $200 million in 2016.
Heart failure, a debilitating and life-threatening condition, affects over 60 million individuals across the world.
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