Medigene: Expansion Of Platform Technology
Edison | Jul 26, 2016 06:13AM ET
Medigene NA O.N. (DE:MDG1k) has announced that it has expanded its TCR platform technology with the grant of a US patent focused on a method for identifying T-cell antigens. This demonstrates Medigene’s continued advancement of its TCR technology, including providing a new source for potential TCR candidates and establishing a more efficient method for identifying tumour-specific antigens. We maintain our rNPV-based valuation at €214m, or €10.8 per share, with upside expected as it executes its clinical strategy.
Expansion of TCR platform technology – US patent
Medigene has expanded its TCR platform technology with the grant of a US patent, which claims a method for the identification of antigens recognised by CD4+ T-cells, including tumour-infiltrating CD4+ T-cells. The patent has a significant period of time to expiry (2030) and is important to Medigene as it offers an effective additional source for potential TCR candidates. It also enables the identification of patient-specific neoantigens seen by CD4+ cells. Neoantigens are potentially good targets for cancer immunotherapy as they are specifically expressed in the tumour, which potentially enables therapies to be specifically targeted.
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