Alnylam Provides Preliminary Q4 Sales For Onpattro & Givlaari

 | Jan 12, 2020 10:17PM ET

Alnylam Pharmaceuticals (NASDAQ:ALNY) announced preliminary global net product revenues for Onpattro (patisiran) and Givlaari (givosiran) for the fourth quarter and updated on the products’ commercial launches. Onpattro is a first-of-its-kind RNA interference (RNAi) therapeutic for the treatment of the polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis in adults. Givlaari is the second RNAi therapeutic from the company approved by the FDA for the treatment of adults with acute hepatic porphyria (AHP).

The preliminary net product revenues for Onpattro for the fourth quarter and 2019 were about $56 million and $166 million, respectively. By the end of 2019, more than 750 patients globally received commercial Onpattro and more than 1,000 patients worldwide, including those in clinical studies and the company’s global Expanded Access Program, were being treated with the drug. The company stated that Onpattro’s new patient growth was significant in the fourth quarter in the United States and the EU, with the trend expected to continue in 2020.

Shares of the company have gained 41.9% in the past year against the Zacks Investment Research

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