Alnylam Focuses On Pipeline Development Amid Competition

 | Sep 18, 2019 11:02PM ET

We issued an updated report on Alnylam Pharmaceuticals Inc. (NASDAQ:ALNY) on Sep 18.

The company’s only approved drug Onpattro’s (patisiran) uptake has been strong since its launch. In August 2018, the FDA approved Onpattro lipid complex injection, a first-of-its-kind RNA interference (RNAi) therapeutic, for the treatment of the polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis in adults. The drug is the first and only FDA-approved treatment for this indication. It should drive revenues for the company as it will be an important treatment option for people suffering from this often fatal disease.

In September 2019, Alnylam announced the initiation of a study of Onpattro to expand the label of the drug. The company initiated a phase III APOLLO-B study on Onpattro for the treatment of ATTR amyloidosis with cardiomyopathy. The initiation of APOLLO-B represents a significant milestone for the company to explore the full potential of Onpattro for patients living with all types of ATTR amyloidosis.

Shares of the company have gained 17.2% year to date against the Original post

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