Acceleron, Fulcrum Therapeutics Ink Deal For Pulmonary Disease

 | Dec 30, 2019 11:01PM ET

Acceleron Pharma Inc. (NASDAQ:XLRN) announced that it has entered into a collaboration and license agreement with Massachusetts-based biopharmaceutical company Fulcrum Therapeutics, Inc. (NASDAQ:FULC) to identify small molecules designed to modulate specific pathways associated within the targeted pulmonary disease space.

Per the agreement, Fulcrum is eligible to receive an upfront payment of $10 million, up to $295 million in milestones for the first commercialized product along with $143.5 million in additional milestones for subsequent products. Fulcrum will also receive mid-single-digit-to-low-double-digit tiered royalties on net sales, upon potential approval.

Moreover, Acceleron will have access to Fulcrum's proprietary product engine and target identification platform and be responsible for all the development and commercialization activities for any candidates identified through this deal.

The partnership is looking to combine Fulcrum’s skill in identifying drug targets based on modulation of genetic pathways with Acceleron’s expertise in TGF-beta superfamily signaling, to develop potential disease-modifying therapies.

Shares of Acceleron inched up 2.9% following this news on Monday. In fact, the stock has rallied 20.8% in the past year compared with Zacks Investment Research

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